Printable Meeting FlierJune Meeting Notice
Thursday, June 14, 2012
Paul Haddad: New Horizons in Ion Chromatography
Paul Haddad
Australian Centre for Research on Separation Science (ACROSS)
Pfizer Analytical Research Centre University of Tasmania
Hobart 7001, Australia
Abstract:
Ion chromatography (IC) is the premier technique for the separation and analysis of inorganic anions and is also highly useful for the determination of other ionic species including inorganic cations, organic acids and bases, carbohydrates, and amino acids. Despite the fact that IC is now a mature technique there have been some very significant developments in the technique over the last five years. These developments will be reviewed, with particular attention to the areas of powerful software to assist in method development, high-speed separations, miniaturisation of columns, multi-dimensional IC separations, and new applications.
Major advances have been made in the design of specialised software for method development in IC. Software for the simulation and optimisation of isocratic separations has been available for several years. However, most IC separations are now performed using gradient elution or using complex elution profiles combining multiple isocratic and gradient steps. There is a need for method development software for such separations. New approaches to this problem will be described, including methodology that enables isocratic retention data to be used to reliably predict retention times (and to therefore optimise separations) for any elution profile comprising isocratic steps and linear gradients. This software enables very rapid selection of optimal elution conditions for a desired group of analytes. Extension of this approach to organic anions of pharmaceutical significance will also be demonstrated.
Polymeric monolithic materials can be used for IC, especially when converted into high-efficiency ion-exchangers by coating with surfactants or functionalised nanoparticles. Alternatively, short, high-efficiency packed columns can be used. These approaches make it possible to construct a two-dimensional IC system having greatly increased peak capacity when compared to conventional IC systems. Recent column developments have also included the introduction of capillary IC, which is capable of continuous operation for long periods. Capillary IC will be discussed, with a focus on method translation from conventional scale to capillary columns.
IC is now being used for a very broad range of new applications and some examples will be discussed to illustrate the manner in which IC continues to develop as an analytical technique. In particular, the use of IC in counter-terrorism applications will be described. Here, IC is used for both pre- and post-blast detection of improvised explosives (“fertiliser bombs”) used frequently in terrorist attacks.
About the Speaker:
Prof. Paul R. Haddad has obtained the degrees of BSc, PhD and DSc from the University of New South Wales. His academic career has been spent at the Australian National University, the University of New South Wales, and since 1992 at the University of Tasmania where he is currently a Distinguished Professor of Chemistry and has just concluded a five-year appointment as an Australian Research Council Federation Fellow. He is also Director of the Australian Centre for Research on Separation Science and Director of the Pfizer Analytical Research Centre. He has a long-standing research interest in analytical separations of inorganic species and has more than 480 publications in this general field. He has also presented in excess of 400 papers at local and international scientific meetings. He is a Fellow of the Australian Academy of Science and the Australian Academy of Technological Sciences and Engineering.
Paul is an editor of Journal of Chromatography A (since 2005), a contributing editor for Trends in Analytical Chemistry (since 2000), and was an editor of Analytica Chimica Acta for 6 years. He is currently a member of the editorial boards of 10 other journals of analytical chemistry or separation science.
Paul is the recipient of a number of national and international awards, including the AJP Martin Gold Medal awarded by the Chromatographic Society, the Royal Society of Chemistry Analytical Separation Methods Award, the RACI HG Smith and Analytical Division medals, the inaugural University of Tasmania Vice-Chancellors Medal for Research Excellence, and the 2011 Marcel Golay Award.
Details:
| Location: | D'ignazio's Towne House |
| Times: | 5:00 PM Executive Committee Meeting 5:45 PM Social "Hour" 6:30 PM Dinner 7:30 PM Presentation |
| Cost: | $30 |
| Dinner Choices: | Chicken Oscar (asparagus, crab meat, Hollandaise sauce) Baked Salmon Eggplant Parmesan |
NOTICE TO STUDENTS AND FACULTY: Full-time students with valid ID may attend dinner meetings at half-price. Faculty members at colleges and universities are urged to bring one or more students to the meeting. If they do, they also can attend at half-price.